PCOS is associated with obesity due to which condition?

• A. hypothyroidism
• B. hyperinsulinemia
• C. hypoandrogenism
• D. hyperestrogenism

Answer: (B)

Polycystic ovary syndrome (PCOS) is closely linked to obesity primarily due to hyperinsulinemia. This condition refers to elevated levels of insulin in the blood, which is commonly observed in individuals with PCOS. The insulin resistance that often accompanies PCOS means that the body's cells do not respond effectively to insulin, leading to higher insulin levels as the pancreas produces more to compensate.

This hyperinsulinemia contributes to weight gain and makes it difficult for individuals with PCOS to lose weight. Increased insulin levels can promote lipid storage and inhibit fat breakdown, further exacerbating obesity. Moreover, insulin impacts ovarian function and can lead to an increase in androgen production, which contributes to the hormonal imbalances observed in PCOS.

Understanding the role of hyperinsulinemia helps clarify the connection between PCOS and obesity, highlighting the metabolic aspects of this condition. This gives insight into addressing weight management and insulin sensitivity as part of treatment plans for individuals with PCOS.