What is one common side effect of long-term NSAID use for menstrual pain?

• A. Increased appetite
• B. Gastrointestinal irritation
• C. Increased energy levels
• D. Better mood regulation

Answer: (B)

Long-term use of NSAIDs (non-steroidal anti-inflammatory drugs) for menstrual pain can lead to gastrointestinal irritation. This is primarily because NSAIDs can disrupt the gastrointestinal mucosal barrier, increasing the risk of irritation to the stomach lining. This irritation can manifest as symptoms including abdominal pain, nausea, and in more severe cases, ulcers or gastrointestinal bleeding.

Other options, such as increased appetite, increased energy levels, or better mood regulation, are not typical side effects associated with NSAID use. In fact, due to gastrointestinal discomfort, patients may experience a decrease in appetite, and the overall impact of chronic pain management with NSAIDs does not inherently translate to improved mood or energy. Understanding the side effects of medications like NSAIDs is crucial for effectively managing pain while also maintaining overall health.