What is the normal range for a woman's estradiol levels during the follicular phase?

• A. 100-500 pg/mL
• B. 30-300 pg/mL
• C. 10-100 pg/mL
• D. 20-200 pg/mL

Answer: (B)

During the follicular phase of a woman's menstrual cycle, estradiol levels typically range from 30 to 300 pg/mL. This range reflects the physiological role of estradiol in promoting the growth and maturation of ovarian follicles in preparation for ovulation. Estradiol, primarily produced by the developing follicles, is essential for regulating the menstrual cycle and ensuring the reproductive system functions properly.

As the follicles mature, they secrete increasing amounts of estradiol, which stimulates the endometrial lining of the uterus to thicken in anticipation of possible implantation of a fertilized egg. This hormonal interplay is crucial for fertility and overall reproductive health.

The provided normal range effectively captures the variations in estradiol levels as they fluctuate throughout the menstrual cycle, particularly during the early part of the follicular phase when levels begin to rise but have not yet reached their peak before ovulation.